WebJul 29, 2024 · MERFISH is a quantitative, genome-scale multiplexed imaging technology for identifying nucleic acids in their native cellular and tissue environment. The technology leverages combinatorial labeling, sequential imaging, and error-tolerant barcoding schemes, to rapidly produce massively multiplexed and accurate measurements of RNA expression. WebNov 1, 2024 · The MERFISH method works by assigning “barcodes” to the cell’s RNAs, hybridizing them with a library of DNA probes to represent these barcodes, and then …
First Platform for Massively Multiplexed Single-Cell In Situ Spatial ...
WebJul 15, 2024 · The company's patented MERFISH technology enables massively multiplexed, genome-scale nucleic acid imaging with high accuracy and unrivaled detection efficiency … WebMERSCOPE combines the power of MERFISH technology with optimized optics to deliver high sensitivity, specificity, information density, and effective multiplexing capacity. cities close to cheyenne wyoming
Zhuang Research Lab
WebMay 22, 2024 · Last, MERFISH utilizes multiple distinct readout sequences, one associated with each bit in the barcodes assigned to RNAs; thus, the amplification method needs to be easily extended to the... WebMERFISH is a technology for spatially resolved RNA profiling of 10s to 10,000s of RNA species in individual cells with high accuracy and high detection efficiency. The standard MERlin MERFISH analysis workflow decodes and segments MERFISH datasets to determine RNA molecules and the cell boundaries represented in the raw images. WebJan 18, 2024 · “Using MERFISH technology, researchers at the Allen Institute were able to gather cellular-resolution spatial transcriptomic data that advanced us significantly closer toward our goal of ... cities close to college station tx